![Epistatic mutations in PUMA BH3 drive an alternate binding mode to potently and selectively inhibit anti-apoptotic Bfl-1 | eLife Epistatic mutations in PUMA BH3 drive an alternate binding mode to potently and selectively inhibit anti-apoptotic Bfl-1 | eLife](https://iiif.elifesciences.org/lax/25541%2Felife-25541-fig8-figsupp4-v1.tif/full/1500,/0/default.jpg)
Epistatic mutations in PUMA BH3 drive an alternate binding mode to potently and selectively inhibit anti-apoptotic Bfl-1 | eLife
![Loss of PUMA protects the ovarian reserve during DNA-damaging chemotherapy and preserves fertility | Cell Death & Disease Loss of PUMA protects the ovarian reserve during DNA-damaging chemotherapy and preserves fertility | Cell Death & Disease](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41419-018-0633-7/MediaObjects/41419_2018_633_Fig1_HTML.jpg)
Loss of PUMA protects the ovarian reserve during DNA-damaging chemotherapy and preserves fertility | Cell Death & Disease
![Epistatic mutations in PUMA BH3 drive an alternate binding mode to potently and selectively inhibit anti-apoptotic Bfl-1 | eLife Epistatic mutations in PUMA BH3 drive an alternate binding mode to potently and selectively inhibit anti-apoptotic Bfl-1 | eLife](https://iiif.elifesciences.org/lax/25541%2Felife-25541-fig1-v1.tif/full/,1500/0/default.jpg)
Epistatic mutations in PUMA BH3 drive an alternate binding mode to potently and selectively inhibit anti-apoptotic Bfl-1 | eLife
![Epistatic mutations in PUMA BH3 drive an alternate binding mode to potently and selectively inhibit anti-apoptotic Bfl-1 | eLife Epistatic mutations in PUMA BH3 drive an alternate binding mode to potently and selectively inhibit anti-apoptotic Bfl-1 | eLife](https://iiif.elifesciences.org/lax/25541%2Felife-25541-fig4-v1.tif/full/,1500/0/default.jpg)
Epistatic mutations in PUMA BH3 drive an alternate binding mode to potently and selectively inhibit anti-apoptotic Bfl-1 | eLife
![PDF) Genome-Wide mRNA Profiling Identifies X-Box-Binding Protein 1 (XBP1) As An IRE1 And PUMA Repressor PDF) Genome-Wide mRNA Profiling Identifies X-Box-Binding Protein 1 (XBP1) As An IRE1 And PUMA Repressor](https://i1.rgstatic.net/publication/351934225_Genome-Wide_mRNA_Profiling_Identifies_X-Box-Binding_Protein_1_XBP1_As_An_IRE1_And_PUMA_Repressor/links/60b09a5292851c168e48274a/largepreview.png)